Dual/"universal" OF app (e.g. Linux OpenGL + Android)?

Say, I have an app where I'd decide to draw the entire UI in OpenGL. Then:

• Is it in principle possible to have this application build from the same codebase for both, say, Linux (as an OpenGL application), and for Android - possibly by using two separate make calls (for instance, something like make linux vs. make android)?
• Is there an existing example for something like this already, which I could consult?

Slightly more complicated - let's say in this application, I'd use some of the Android API, say screen rotation. Would it be in principle possible to build a Linux OpenGL version out of it, such that the Android-specific functionality will be automatically removed, without placing #ifdefs manually?

Thanks in advance for any pointers,
Cheers!